In Louisiana, the thirty-five year old single mother Lavina delivers a baby boy and a monster in the evil Whateley House. Ten years later, Dr. Henry Armitage and his assistant Professor Fay Morgan discover that the page 751 of every copy of the Necronomicon is missing and The Black Brotherhood has summoned the gate keeper Yog Sothoth to leave the portal opened to the demons and ancient gods. They invite the arrogant and skeptical Professor Walter Rice that can translate the Necronomicon to help them to seek the book. Meanwhile Lavina's son Wilbur Whateley ages very fast and seeks the missing page to open the portal.

Corin Nemec (Mansquito, SS Doomtrooper) co-stars alongside Carpenter as TV ghost hunters that enter a reportedly haunted house that may prove to be the death of them.

A group of talented but rebellious 'rock-star scientists' find themselves in a race against time to save Earth when a comet makes an unexpected turn towards our blue planet where all life may cease to exist within days if our small town heroes fail to find a solution.